Original Investigation | Mrch 2014
Shailesh Agarwal, MD1; Lisa Pappas,
MS2; Leigh Neumayer, MD3; Kristine Kokeny, MD4; Jayant Agarwal, MD3 [+] Author Affiliations
Surg. 2014;149(3):267-274. doi:10.1001/jamasurg.2013.3049.
ABSTRACT | METHODS | RESULTS | CONCLUSIONS | CONCLUSIONS | ARTICLE INFORMATION | REFERENCES
To our knowledge, there are no recent studies that directly compare survival after breast conservation therapy (BCT) vs mastectomy.
Objective To compare the breast cancer?specific survival rates of patients undergoing
BCT, mastectomy alone, or mastectomy with radiation using a contemporary cohort of patients.
Setting, and Participants We performed univariate, multivariate logistic regression, and propensity analyses to
compare the hazard of death for female patients with early-stage invasive ductal carcinoma treated with BCT, mastectomy alone,
or mastectomy with radiation during the period from 1998 to 2008. The data were extracted from the Surveillance, Epidemiology,
and End Results database. Early-stage breast cancer was defined as having a tumor size of 4 cm or smaller with 3 or less positive
Exposure Breast conservation therapy, mastectomy alone, or mastectomy